Across TCGA cell cohorts, FICD mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FICD-associated genes across cancer lineages are FTHL17, OR1L3, and OR2J1. Each is linked with FICD in more than 1 cancer types. Because this analysis shows association rather than direction, both FICD-to-partner and partner-to-FICD results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FICD→partner) and Y-score (partner→FICD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FTHL17 →	+0.060	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR1L3 →	+0.017	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR2J1 →	+0.005	+5.022	<.001	.002	3	1
LARGE_INTESTINE	OR2A25 →	+0.029	+4.930	<.001	.001	3	1
LARGE_INTESTINE	PPP4R3C →	+0.019	+4.273	.004	.006	3	1
OVARY	VCY1B →	+0.275	+4.029	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

FICD survival (RNA) · tumor vs normal (RNA) · all FICD data types