FIBP

Across TCGA cell cohorts, FIBP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,085 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FIBP-associated GO terms across cancer lineages are Regulation of attachment of mitotic spindle microtubules to kinetochore, Positive regulation of attachment of mitotic spindle microtubules to kinetochore, and Regulation of metaphase plate congression. Each is linked with FIBP in more than 10 cancer types. Because this analysis shows association rather than direction, both FIBP-to-partner and partner-to-FIBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of attachment of mitotic spindle microtubules to kinetochore grouped by FIBP-low versus FIBP-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FIBP→partner) and Y-score (partner→FIBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.181	+0.818	.001	.007	3	11
LUNG_NSCLC_LUSC	Positive regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.186	+0.859	<.001	.004	3	11
LUNG_NSCLC_LUSC	Regulation of metaphase plate congression →	+0.136	+0.839	.001	.003	3	10
SKIN	Positive regulation of attachment of spindle microtubules to kinetochore →	+0.121	+0.457	.007	.007	3	9
BLOOD_Myeloma	Positive regulation of mitotic cytokinesis →	+0.124	+0.557	.005	.006	3	9
LIVER	Primary alcohol metabolic process →	-0.138	-0.865	.005	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,085 associations by consensus.

Regulation of attachment of mitotic spindle microtubules to kinetochore by FIBP expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →