FIBP

Across TCGA pan-cancer cohorts, FIBP RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated FIBP data layer compared with 5 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher FIBP RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FIBP expression acts as an unfavorable survival marker, although some lineages such as THCA and STAD show a favorable association.

ACC, KICH, and MESO are the cancer types where FIBP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.773	0.963	<.001	120	view →
KICH	OS	Tertile	II,III,IV	0.582	1.000	.001	81	view →
MESO	OS	Median	All	0.432	0.648	<.001	74	view →
LIHC	OS	Median	All	0.434	0.586	<.001	50	view →
LAML	DFS	Median	All	0.321	0.584	<.001	48	view →
UVM	DFS	Quartile	All	0.375	0.759	.004	39	view →
LGG	OS	Quartile	All	0.803	0.943	.001	22	view →
READ	OS	Quartile	IV	0.371	0.911	.002	20	view →
THCA	OS	Median	III,IV	1.000	0.648	.022	20	view →
HNSC	OS	Median	All	0.292	0.522	.005	19	view →
BLCA	OS	Quartile	All	0.483	0.752	.013	18	view →
SKCM	OS	Quartile	All	0.234	0.541	.006	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

FIBP–ACC (OS)

Open the ACC breakdown →