FIBP

Across TCGA cell cohorts, FIBP mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FIBP-associated genes across cancer lineages are IQCF3, KRTAP19-3, and IZUMO2. Each is linked with FIBP in more than 1 cancer types. Because this analysis shows association rather than direction, both FIBP-to-partner and partner-to-FIBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IQCF3 grouped by FIBP-low versus FIBP-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FIBP→partner) and Y-score (partner→FIBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	IQCF3 →	+0.049	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	KRTAP19-3 →	+0.132	+5.228	<.001	.005	3	1
BLOOD_Lymphoma	IZUMO2 →	+0.036	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	MS4A10 →	+0.006	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	FAM162B →	+0.731	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	KRTAP6-1 →	+0.104	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

IQCF3 by FIBP expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →