FIBCD1

Across TCGA cell cohorts, FIBCD1 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FIBCD1-associated genes across cancer lineages are MMP26, UTF1, and C10orf53. Each is linked with FIBCD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FIBCD1-to-partner and partner-to-FIBCD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP26 grouped by FIBCD1-low versus FIBCD1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FIBCD1→partner) and Y-score (partner→FIBCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MMP26 →	+0.033	+3.217	<.001	.006	3	1
LARGE_INTESTINE	UTF1 →	+0.015	+3.217	<.001	.006	3	1
LARGE_INTESTINE	C10orf53 →	+0.013	+3.217	<.001	.006	3	1
BLOOD_Leukemia	KCNA10 →	+0.004	+4.539	.009	.007	3	1
BLOOD_Leukemia	OR8D4 →	+0.004	+4.539	<.001	.007	3	1
BLOOD_Leukemia	CSHL1 →	+0.016	+4.539	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

MMP26 by FIBCD1 expression — LARGE_INTESTINE

Explore this box plot interactively →