FHAD1

Across TCGA patient cohorts, FHAD1 mutation is significantly associated with the RNA expression of many other genes, with 3,792 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FHAD1-associated genes across cancer lineages are TRDV3, SENP3-EIF4A1, and ME2. Each is linked with FHAD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FHAD1-to-partner and partner-to-FHAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRDV3 grouped by FHAD1-low versus FHAD1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FHAD1→partner) and Y-score (partner→FHAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TRDV3 →	+0.586	+3.469	.001	.002	3	3
CESC	SENP3-EIF4A1 →	+0.184	+3.346	<.001	.006	3	3
CESC	ME2 →	+0.751	+3.199	<.001	.009	3	3
UCEC	SRCIN1 →	-0.622	-2.574	<.001	<.001	3	3
UCEC	TRMU →	+0.437	+3.353	<.001	<.001	3	3
CESC	NUP88 →	+0.511	+3.489	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,792 associations by consensus.

TRDV3 by FHAD1 expression — CESC

Explore this box plot interactively →