FHAD1

Across TCGA cell cohorts, FHAD1 mutation is significantly associated with the RNA expression of many other genes, with 159 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FHAD1-associated genes across cancer lineages are KIR2DS4, ATP6V1G3, and TRIM49. Each is linked with FHAD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FHAD1-to-partner and partner-to-FHAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIR2DS4 grouped by FHAD1-low versus FHAD1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FHAD1→partner) and Y-score (partner→FHAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	KIR2DS4 →	+0.132	+2.564	.006	.007	3	2
LUNG_NSCLC_LUSC	ATP6V1G3 →	+0.260	+4.108	.001	.005	3	1
URINARY_TRACT	TRIM49 →	+0.013	+5.087	<.001	.004	3	1
URINARY_TRACT	PRORY →	+0.343	+5.087	<.001	.004	3	1
URINARY_TRACT	RBMY1E →	+0.143	+5.087	<.001	.004	3	1
LUNG_SCLC	OR14K1 →	+0.117	+4.269	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 159 associations by consensus.

KIR2DS4 by FHAD1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →