FH

Across TCGA patient cohorts, FH RNA expression is significantly associated with the protein abundance of many other proteins, with 16,201 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FH-associated proteins across cancer lineages are CACYBP, ADAR, and PARP1. Each is linked with FH in more than 7 cancer types. Because this analysis shows association rather than direction, both FH-to-partner and partner-to-FH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FH versus CACYBP in LSCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FH→partner) and Y-score (partner→FH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CACYBP →	+0.392	+0.481	<.001	<.001	3	8
BRCA	ADAR →	+0.309	+0.397	<.001	<.001	3	8
OV	PARP1 →	+0.524	+0.558	.001	.002	3	8
HNSC	CTR9 →	+0.188	+1.269	<.001	.002	3	7
COAD	C1orf35 →	+0.584	+0.538	<.001	.002	3	7
OV	BROX →	+0.555	+0.549	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,201 associations by consensus.

FH vs CACYBP — LSCC

Explore this scatter interactively →