FGL2

Across TCGA patient cohorts, FGL2 protein abundance is significantly associated with the RNA expression of many other genes, with 17,913 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FGL2-associated genes across cancer lineages are CCR7, THEMIS, and CRTAM. Each is linked with FGL2 in more than 9 cancer types. Because this analysis shows association rather than direction, both FGL2-to-partner and partner-to-FGL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGL2 versus CCR7 in HNSC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGL2→partner) and Y-score (partner→FGL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CCR7 →	+1.033	+0.515	<.001	<.001	3	10
UCEC	THEMIS →	+1.108	+0.875	<.001	.002	3	10
UCEC	CRTAM →	+0.696	+0.722	<.001	<.001	3	9
OV	CD5 →	+1.161	+0.660	<.001	.002	3	9
HNSC	ZAP70 →	+0.847	+0.462	<.001	<.001	3	9
LSCC	ZNF831 →	+0.808	+0.577	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,913 associations by consensus.

FGL2 vs CCR7 — HNSC

Explore this scatter interactively →