FGL1

Across TCGA patient cohorts, FGL1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,488 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FGL1-associated genes across cancer lineages are IL1B, IL6, and SOCS3. Each is linked with FGL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FGL1-to-partner and partner-to-FGL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGL1 versus IL1B in HNSC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGL1→partner) and Y-score (partner→FGL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	IL1B →	+1.645	+0.704	<.001	.003	3	3
LSCC	IL6 →	+1.623	+0.544	<.001	<.001	3	3
HNSC	SOCS3 →	+0.948	+0.676	.001	.001	3	3
HNSC	RN7SKP124 →	-0.812	-0.472	.008	.005	3	3
HNSC	RPS3AP13 →	-0.555	-0.629	.002	.001	3	3
HNSC	RPSAP41 →	-0.282	-0.618	.007	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,488 associations by consensus.

FGL1 vs IL1B — HNSC

Explore this scatter interactively →