FGFR4

Across TCGA patient cohorts, FGFR4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,703 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FGFR4-associated proteins across cancer lineages are PLEKHA6_S808, SERPINH1, and COQ8A. Each is linked with FGFR4 in more than 4 cancer types. Because this analysis shows association rather than direction, both FGFR4-to-partner and partner-to-FGFR4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGFR4 versus PLEKHA6_S808 in UCEC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FGFR4→partner) and Y-score (partner→FGFR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PLEKHA6_S808 →	+0.559	+0.826	<.001	<.001	3	5
LSCC	SERPINH1 →	-0.464	-0.746	<.001	.001	3	4
COAD	COQ8A →	+0.310	+0.865	.001	.001	3	4
CCRCC	CTHRC1 →	-0.695	-0.906	.003	.001	3	4
UCEC	ENDOD1 →	-0.447	-1.111	<.001	<.001	3	4
LSCC	MYEF2 →	+0.828	+0.885	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,703 associations by consensus.

FGFR4 vs PLEKHA6_S808 — UCEC

Explore this scatter interactively →