FGFR2

Across TCGA patient cohorts, FGFR2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,766 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FGFR2-associated genes across cancer lineages are RPLP1, CALN1, and SYP. Each is linked with FGFR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both FGFR2-to-partner and partner-to-FGFR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGFR2 versus RPLP1 in HNSC, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGFR2→partner) and Y-score (partner→FGFR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPLP1 →	+2.120	+1.429	.002	<.001	3	3
UCEC	CALN1 →	+1.423	+0.803	.002	<.001	3	3
GBM	SYP →	+1.166	+0.505	<.001	.001	3	3
HNSC	C2orf42 →	+0.692	+1.063	.001	.006	3	3
HNSC	LRP4 →	+1.783	+1.439	.003	<.001	3	3
HNSC	KAT14 →	+0.764	+1.065	.002	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,766 associations by consensus.

FGFR2 vs RPLP1 — HNSC

Explore this scatter interactively →