FGFR1OP2

Across TCGA patient cohorts, FGFR1OP2 mutation is significantly associated with the RNA expression of many other genes, with 562 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FGFR1OP2-associated genes across cancer lineages are MIR7702, RNU6-669P, and MICE. Each is linked with FGFR1OP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGFR1OP2-to-partner and partner-to-FGFR1OP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7702 grouped by FGFR1OP2-low versus FGFR1OP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGFR1OP2→partner) and Y-score (partner→FGFR1OP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7702 →	+0.202	+4.060	<.001	.006	3	2
UCEC	RNU6-669P →	+0.256	+2.380	.003	.005	3	2
UCEC	MICE →	+0.325	+2.324	.001	.005	3	1
UCEC	TAF9 →	+0.621	+2.606	<.001	.005	3	1
UCEC	IGHV2-70 →	+1.713	+3.000	<.001	.001	3	1
UCEC	H2AC14 →	+0.815	+2.238	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 562 associations by consensus.

MIR7702 by FGFR1OP2 expression — UCEC

Explore this box plot interactively →