FGFR1OP2

Across TCGA pan-cancer cohorts, FGFR1OP2 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated FGFR1OP2 data layer compared with 1 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher FGFR1OP2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated FGFR1OP2 expression acts as an unfavorable survival marker, although some lineages such as SKCM and KIRC show a favorable association.

SKCM, UVM, and CESC are the cancer types where FGFR1OP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.824	0.737	.001	68	view →
UVM	DFS	Quartile	III,IV	0.170	0.832	<.001	34	view →
CESC	OS	Median	III,IV	0.236	0.740	.011	30	view →
KIRC	DFS	Median	All	0.859	0.728	.008	24	view →
CHOL	DFS	Median	All	0.626	0.195	.018	21	view →
LIHC	OS	Median	All	0.732	0.817	.014	17	view →
KICH	DFS	Median	II,III,IV	0.564	0.920	.004	17	view →
ACC	OS	Quartile	All	0.637	0.895	.003	14	view →
THYM	DFS	Quartile	II,III,IV	1.000	0.460	.019	9	view →
PAAD	OS	Tertile	II,III,IV	0.528	0.307	.009	6	view →
LUSC	OS	Median	II,III,IV	0.525	0.764	.031	5	view →
COAD	OS	Quartile	II,III,IV	0.942	0.769	.022	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

FGFR1OP2–SKCM (OS)

Open the SKCM breakdown →