FGFBP3

Across TCGA patient cohorts, FGFBP3 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FGFBP3-associated genes across cancer lineages are OR10A3, C7orf77, and ANKRD60. Each is linked with FGFBP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGFBP3-to-partner and partner-to-FGFBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10A3 grouped by FGFBP3-low versus FGFBP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGFBP3→partner) and Y-score (partner→FGFBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR10A3 →	+0.175	+4.184	<.001	.003	3	1
UCEC	C7orf77 →	+0.177	+3.719	<.001	.008	3	1
UCEC	ANKRD60 →	+0.093	+4.267	<.001	.009	3	1
UCEC	RN7SL804P →	+0.248	+3.840	.009	.007	3	1
UCEC	MIR3909 →	+0.640	+4.741	<.001	.001	3	1
UCEC	MIR3135A →	+0.648	+4.038	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

OR10A3 by FGFBP3 expression — UCEC

Explore this box plot interactively →