FGFBP3

Across TCGA cell cohorts, FGFBP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,706 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FGFBP3-associated GO terms across cancer lineages are Positive regulation of fibroblast growth factor receptor signaling pathway, Cell adhesion mediated by integrin, and Regulation of vasculature development. Each is linked with FGFBP3 in more than 11 cancer types. Because this analysis shows association rather than direction, both FGFBP3-to-partner and partner-to-FGFBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of fibroblast growth factor receptor signaling pathway grouped by FGFBP3-low versus FGFBP3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGFBP3→partner) and Y-score (partner→FGFBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of fibroblast growth factor receptor signaling pathway →	-0.166	-0.773	<.001	.001	2	12
BONE	Cell adhesion mediated by integrin →	-0.256	-0.593	<.001	.005	2	12
BONE	Regulation of vasculature development →	-0.113	-0.624	.001	.007	2	11
SOFT_TISSUE	Substrate adhesion-dependent cell spreading →	-0.144	-3.033	.001	<.001	3	9
SOFT_TISSUE	Regulation of adaptive immune response →	-0.054	-2.140	<.001	.001	3	9
BONE	Extracellular matrix organization →	-0.213	-0.556	<.001	.006	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,706 associations by consensus.

Positive regulation of fibroblast growth factor receptor signaling pathway by FGFBP3 expression — BONE

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