FGFBP3

Across TCGA cell cohorts, FGFBP3 mutation is significantly associated with the mutation status of many other genes, with 188 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FGFBP3-associated genes across cancer lineages are KCNA4, USP7, and CDH10. Each is linked with FGFBP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGFBP3-to-partner and partner-to-FGFBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNA4 grouped by FGFBP3-low versus FGFBP3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGFBP3→partner) and Y-score (partner→FGFBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KCNA4 →	+4.014	+4.969	.008	.008	1	2
BLOOD_Lymphoma	USP7 →	+4.014	+4.969	.008	.008	1	2
BLOOD_Leukemia	CDH10 →	+4.000	+5.050	.008	.008	1	2
BLOOD_Leukemia	ITGA8 →	+4.736	+5.560	.003	.003	1	2
BLOOD_Lymphoma	ZNF14 →	+5.014	+5.584	.003	.003	1	2
BLOOD_Lymphoma	KDM5C →	+4.429	+5.247	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 188 associations by consensus.

KCNA4 by FGFBP3 expression — BLOOD_Lymphoma

Explore this box plot interactively →