FGFBP2

Across TCGA patient cohorts, FGFBP2 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FGFBP2-associated genes across cancer lineages are PRAS40_pT246 and Tuberin_pT1462. Each is linked with FGFBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGFBP2-to-partner and partner-to-FGFBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAS40_pT246 grouped by FGFBP2-low versus FGFBP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGFBP2→partner) and Y-score (partner→FGFBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRAS40_pT246 →	+0.362	+2.820	<.001	.036	3	1
UCEC	Tuberin_pT1462 →	+0.407	+2.817	.003	.036	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PRAS40_pT246 by FGFBP2 expression — UCEC

Explore this box plot interactively →