FGFBP2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FGFBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,190 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FGFBP2-associated GO terms across cancer lineages are Sterol metabolic process, Negative regulation of axon regeneration, and Positive regulation of T cell activation. Each is linked with FGFBP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both FGFBP2-to-partner and partner-to-FGFBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sterol metabolic process grouped by FGFBP2-low versus FGFBP2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGFBP2→partner) and Y-score (partner→FGFBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINSterol metabolic process →+0.076+2.372.001<.00134
SKINNegative regulation of axon regeneration →+0.184+2.204<.001<.00134
SKINPositive regulation of T cell activation →+0.055+1.862<.001.00234
BREASTOptic nerve development →-0.482-0.248.003.00733
BREASTCellular response to insulin stimulus →+0.029+0.399.007.00124
BREASTRegulation of postsynaptic membrane potential →-0.061-0.390.002.00124
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,190 associations by consensus.

Sterol metabolic process by FGFBP2 expression — SKIN

Box plot of Sterol metabolic process in FGFBP2-low vs FGFBP2-high samples in SKIN.

Explore this box plot interactively →

Exploration