FGFBP2

Across TCGA cell cohorts, FGFBP2 mutation is significantly associated with the mutation status of many other genes, with 259 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FGFBP2-associated genes across cancer lineages are HIPK3, RBMXL3, and CCDC80. Each is linked with FGFBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGFBP2-to-partner and partner-to-FGFBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HIPK3 grouped by FGFBP2-low versus FGFBP2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGFBP2→partner) and Y-score (partner→FGFBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	HIPK3 →	+5.772	+5.772	.002	.002	1	2
LUNG_NSCLC_LUAD	RBMXL3 →	+4.187	+5.000	.008	.008	1	2
SKIN	CCDC80 →	+4.824	+5.392	.004	.004	1	2
SKIN	NSD3 →	+4.824	+5.392	.004	.004	1	2
LUNG_NSCLC_LUAD	DPYSL3 →	+4.187	+5.000	.008	.008	1	1
LUNG_NSCLC_LUAD	KIRREL2 →	+4.187	+5.000	.008	.008	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 259 associations by consensus.

HIPK3 by FGFBP2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →