FGFBP1

Across TCGA patient cohorts, FGFBP1 mutation is significantly associated with the RNA expression of many other genes, with 346 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible FGFBP1-associated genes across cancer lineages are TGIF2LY, RNU6-1169P, and RNU6-1246P. Each is linked with FGFBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGFBP1-to-partner and partner-to-FGFBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TGIF2LY grouped by FGFBP1-low versus FGFBP1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGFBP1→partner) and Y-score (partner→FGFBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	TGIF2LY →	+0.637	+4.567	<.001	.004	3	2
LIHC	RNU6-1169P →	+0.289	+5.479	<.001	.002	3	2
SKCM	RNU6-1246P →	+0.083	+4.003	<.001	.006	3	2
LUAD	CYCTP →	+0.113	+5.197	<.001	.003	3	2
SKCM	SRI →	+0.491	+2.826	.003	.001	3	2
SKCM	MRC1 →	+1.048	+3.331	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 346 associations by consensus.

TGIF2LY by FGFBP1 expression — LIHC

Explore this box plot interactively →