FGFBP1

Across TCGA pan-cancer cohorts, FGFBP1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of FGFBP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where FGFBP1 RNA is repressed in tumor relative to normal tissue. In most cancer types FGFBP1 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and BRCA are the cancer types where FGFBP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FGFBP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	II,III,IV	−1.711	<.001	12	view →
KICH	Female	II,III,IV	−2.537	<.001	10	view →
BRCA	All	III,IV	−3.117	<.001	8	view →
LUSC	Female	II,III,IV	+4.214	<.001	6	view →
COAD	All	All	−1.219	<.001	4	view →
LUAD	Female	II,III,IV	+1.682	.004	3	view →
PAAD	All	All	+3.480	.019	2	view →
PRAD	All	All	−0.925	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

FGFBP1–KIRC

Open the KIRC breakdown →