FGF7

Across TCGA cell cohorts, FGF7 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,835 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FGF7-associated GO terms across cancer lineages are Vesicle cargo loading, Positive regulation of epithelial cell proliferation involved in lung morphogenesis, and Maintenance of postsynaptic density structure. Each is linked with FGF7 in more than 5 cancer types. Because this analysis shows association rather than direction, both FGF7-to-partner and partner-to-FGF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle cargo loading grouped by FGF7-low versus FGF7-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF7→partner) and Y-score (partner→FGF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Vesicle cargo loading →	+0.097	+1.249	<.001	.005	3	5
BONE	Positive regulation of epithelial cell proliferation involved in lung morphogenesis →	-0.219	-2.513	<.001	.008	2	5
BONE	Maintenance of postsynaptic density structure →	-0.187	-3.717	.007	.007	3	4
OESOPHAGUS	Negative regulation of synaptic plasticity →	-1.304	-0.124	.001	.004	3	4
CNS	Negative regulation of synaptic transmission, glutamatergic →	-0.323	-1.471	.005	<.001	3	4
SKIN	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.057	-0.718	.006	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,835 associations by consensus.

Vesicle cargo loading by FGF7 expression — CNS

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