FGF6

Across TCGA patient cohorts, FGF6 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,568 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FGF6-associated GO terms across cancer lineages are Actomyosin structure organization, Developmental cell growth, and Retrograde transport, endosome to Golgi. Each is linked with FGF6 in more than 13 cancer types. Because this analysis shows association rather than direction, both FGF6-to-partner and partner-to-FGF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actomyosin structure organization grouped by FGF6-low versus FGF6-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF6→partner) and Y-score (partner→FGF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Actomyosin structure organization →	+0.062	+0.086	<.001	<.001	3	14
STAD	Developmental cell growth →	+0.052	+0.077	<.001	<.001	3	14
STAD	Retrograde transport, endosome to Golgi →	+0.065	+0.088	<.001	<.001	3	13
STAD	Negative regulation of TOR signaling →	+0.069	+0.092	<.001	<.001	3	13
STAD	Positive regulation of intracellular transport →	+0.067	+0.080	<.001	<.001	3	13
STAD	Regulation of protein depolymerization →	+0.057	+0.087	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,568 associations by consensus.

Actomyosin structure organization by FGF6 expression — STAD

Explore this box plot interactively →