FGF6

Across TCGA patient cohorts, FGF6 mutation is significantly associated with the RNA expression of many other genes, with 1,868 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FGF6-associated genes across cancer lineages are RN7SKP169, MIR4515, and RNA5SP412. Each is linked with FGF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGF6-to-partner and partner-to-FGF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP169 grouped by FGF6-low versus FGF6-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF6→partner) and Y-score (partner→FGF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RN7SKP169 →	+0.229	+6.479	<.001	.001	3	2
BRCA	MIR4515 →	+0.317	+4.386	<.001	.008	3	2
UCEC	RNA5SP412 →	+0.788	+2.382	<.001	<.001	3	2
UCEC	CHEK1 →	+0.665	+3.606	.001	.001	3	2
UCEC	CENPU →	+0.753	+2.534	.001	.001	3	2
UCEC	CENPH →	+0.624	+2.708	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,868 associations by consensus.

RN7SKP169 by FGF6 expression — LIHC

Explore this box plot interactively →