FGF6

Across TCGA cell cohorts, FGF6 RNA expression is significantly associated with the go_rna of many other GO terms, with 608 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FGF6-associated GO terms across cancer lineages are Endochondral ossification, Spinal cord development, and Replacement ossification. Each is linked with FGF6 in more than 2 cancer types. Because this analysis shows association rather than direction, both FGF6-to-partner and partner-to-FGF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endochondral ossification grouped by FGF6-low versus FGF6-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF6→partner) and Y-score (partner→FGF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Endochondral ossification →	+0.256	+0.631	<.001	<.001	3	3
BLOOD_Leukemia	Spinal cord development →	+0.055	+0.531	<.001	.003	3	3
BLOOD_Leukemia	Replacement ossification →	+0.256	+0.631	<.001	<.001	3	3
BLOOD_Leukemia	Hyperosmotic salinity response →	+0.142	+0.339	.001	.009	3	3
BLOOD_Leukemia	Cellular hyperosmotic salinity response →	+0.142	+0.339	.001	.009	3	3
BLOOD_Leukemia	Specification of animal organ identity →	+0.778	+0.342	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 608 associations by consensus.

Endochondral ossification by FGF6 expression — BLOOD_Leukemia

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