FGF5

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FGF5 protein abundance is significantly associated with the RNA expression of many other genes, with 1,289 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FGF5-associated genes across cancer lineages are GINS1, UQCC1, and CCDC77. Each is linked with FGF5 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGF5-to-partner and partner-to-FGF5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGF5 versus GINS1 in LUAD, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF5→partner) and Y-score (partner→FGF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADGINS1 →+1.860+0.951<.001<.00132
PDACUQCC1 →+0.466+1.366.005.00332
LUADCCDC77 →+0.764+0.995.005<.00132
LUADAUNIP →+1.114+0.948.006.00132
PDACCCNB1 →+1.423+1.493.003.00232
LUADSUV39H2 →+0.825+0.938.002.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,289 associations by consensus.

FGF5 vs GINS1 — LUAD

Per-sample scatter of FGF5 vs GINS1 in LUAD (Pearson r = 0.48).

Explore this scatter interactively →

Exploration