FGF5

Across TCGA cell cohorts, FGF5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,436 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FGF5-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Establishment of epithelial cell apical/basal polarity, and Positive regulation of cell-substrate junction organization. Each is linked with FGF5 in more than 11 cancer types. Because this analysis shows association rather than direction, both FGF5-to-partner and partner-to-FGF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by FGF5-low versus FGF5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF5→partner) and Y-score (partner→FGF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of focal adhesion assembly →	+0.172	+2.594	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Establishment of epithelial cell apical/basal polarity →	+0.217	+2.603	.004	.009	3	11
BONE	Positive regulation of cell-substrate junction organization →	+0.152	+2.605	<.001	<.001	3	11
BONE	Regulation of intracellular transport →	+0.066	+2.779	.001	.001	3	11
BONE	Regulation of intracellular protein transport →	+0.061	+2.236	.005	.008	3	11
BONE	Cortisol metabolic process →	-1.177	-2.297	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,436 associations by consensus.

Positive regulation of focal adhesion assembly by FGF5 expression — BONE

Explore this box plot interactively →