FGF4

Across TCGA pan-cancer cohorts, FGF4 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated FGF4 data layer compared with 17 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher FGF4 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated FGF4 expression acts as an unfavorable survival marker.

KIRP, BLCA, and SKCM are the cancer types where FGF4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	All	0.115	0.867	<.001	24	view →
BLCA	OS	Median	All	0.212	0.720	.007	12	view →
SKCM	DFS	Median	All	0.224	0.622	.020	6	view →
LUAD	OS	Median	II,III,IV	0.237	0.709	.039	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

FGF4–KIRP (DFS)

Open the KIRP breakdown →