FGF4

Across TCGA patient cohorts, FGF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,950 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FGF4-associated GO terms across cancer lineages are Somite development, DNA strand elongation involved in DNA replication, and Telomere maintenance. Each is linked with FGF4 in more than 10 cancer types. Because this analysis shows association rather than direction, both FGF4-to-partner and partner-to-FGF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Somite development grouped by FGF4-low versus FGF4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF4→partner) and Y-score (partner→FGF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Somite development →	+0.047	+0.208	<.001	<.001	3	11
STAD	DNA strand elongation involved in DNA replication →	+0.129	+0.237	<.001	<.001	3	9
STAD	Telomere maintenance →	+0.097	+0.235	<.001	<.001	3	9
STAD	Translational initiation →	+0.054	+0.154	<.001	<.001	3	8
STAD	Positive regulation of cell cycle phase transition →	+0.051	+0.114	<.001	.005	3	8
STAD	Positive regulation of mitotic cell cycle phase transition →	+0.066	+0.188	<.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,950 associations by consensus.

Somite development by FGF4 expression — STAD

Explore this box plot interactively →