FGF20

Across TCGA pan-cancer cohorts, FGF20 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated FGF20 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher FGF20 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated FGF20 expression acts as an unfavorable survival marker.

HNSC, LIHC, and STAD are the cancer types where FGF20 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.087	0.710	<.001	36	view →
LIHC	DFS	Median	All	0.103	0.545	<.001	33	view →
STAD	OS	Median	All	0.096	0.688	<.001	12	view →
SKCM	DFS	Median	III,IV	0.088	0.613	.018	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

FGF20–HNSC (DFS)

Open the HNSC breakdown →