FGF20

Across TCGA cell cohorts, FGF20 RNA expression is significantly associated with the go_rna of many other GO terms, with 531 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible FGF20-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Regulation of myoblast fusion, and Mitochondrial electron transport, cytochrome c to oxygen. Each is linked with FGF20 in more than 6 cancer types. Because this analysis shows association rather than direction, both FGF20-to-partner and partner-to-FGF20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by FGF20-low versus FGF20-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF20→partner) and Y-score (partner→FGF20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.071	+0.231	.001	.001	3	7
LUNG_SCLC	Regulation of myoblast fusion →	+0.079	+0.209	.001	.008	3	6
LUNG_SCLC	Mitochondrial electron transport, cytochrome c to oxygen →	+0.088	+0.298	<.001	.005	3	6
SOFT_TISSUE	Proton motive force-driven ATP synthesis →	+0.052	+0.481	.003	.005	3	5
SOFT_TISSUE	Proton motive force-driven mitochondrial ATP synthesis →	+0.054	+0.494	.002	.004	3	5
CNS	Telomerase holoenzyme complex assembly →	+0.023	+0.170	.005	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 531 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by FGF20 expression — LUNG_SCLC

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