FGF18

Across TCGA cell cohorts, FGF18 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FGF18-associated genes across cancer lineages are OR10T2 and KRTAP5-6. Each is linked with FGF18 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGF18-to-partner and partner-to-FGF18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10T2 grouped by FGF18-low versus FGF18-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF18→partner) and Y-score (partner→FGF18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR10T2 →	+0.683	+4.276	<.001	.007	3	1
BLOOD_Leukemia	KRTAP5-6 →	+0.312	+4.874	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR10T2 by FGF18 expression — BLOOD_Leukemia

Explore this box plot interactively →