FGF12

Across TCGA cell cohorts, FGF12 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FGF12-associated genes across cancer lineages are TRIML1, PRSS54, and LHCGR. Each is linked with FGF12 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGF12-to-partner and partner-to-FGF12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIML1 grouped by FGF12-low versus FGF12-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF12→partner) and Y-score (partner→FGF12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	TRIML1 →	+0.159	+3.684	<.001	.001	3	1
LARGE_INTESTINE	PRSS54 →	+0.035	+3.345	<.001	.007	3	1
LARGE_INTESTINE	LHCGR →	+0.034	+3.882	<.001	.001	3	1
LARGE_INTESTINE	MAJIN →	+0.108	+3.554	<.001	.007	3	1
LARGE_INTESTINE	C14orf180 →	+0.102	+3.155	.002	.008	3	1
LARGE_INTESTINE	OR6Q1 →	+0.015	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

TRIML1 by FGF12 expression — LUNG_SCLC

Explore this box plot interactively →