FGF11

Across TCGA cell cohorts, FGF11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,798 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FGF11-associated GO terms across cancer lineages are Regulation of translation at presynapse, modulating synaptic transmission, Regulation of translation at synapse, and Regulation of translation at presynapse. Each is linked with FGF11 in more than 9 cancer types. Because this analysis shows association rather than direction, both FGF11-to-partner and partner-to-FGF11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translation at presynapse, modulating synaptic transmission grouped by FGF11-low versus FGF11-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF11→partner) and Y-score (partner→FGF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of translation at presynapse, modulating synaptic transmission →	+0.122	+0.833	<.001	.001	3	10
PANCREAS	Regulation of translation at synapse →	+0.111	+0.780	<.001	.003	3	10
PANCREAS	Regulation of translation at presynapse →	+0.122	+0.833	<.001	.001	3	10
BREAST	mRNA transport →	+0.091	+1.109	<.001	.004	3	10
LUNG_SCLC	Regulation of translation at synapse, modulating synaptic transmission →	+0.104	+1.612	.004	.006	3	9
STOMACH	Regulation of myoblast fusion →	+0.131	+2.020	.002	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,798 associations by consensus.

Regulation of translation at presynapse, modulating synaptic transmission by FGF11 expression — PANCREAS

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