FGF11

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FGF11 protein abundance is significantly associated with the go_rna of many other GO terms, with 439 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FGF11-associated GO terms across cancer lineages are Cellular response to type III interferon, Response to hydrostatic pressure, and Type III interferon-mediated signaling pathway. Each is linked with FGF11 in more than 2 cancer types. Because this analysis shows association rather than direction, both FGF11-to-partner and partner-to-FGF11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to type III interferon grouped by FGF11-low versus FGF11-high in BLOOD_Lymphoma.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF11→partner) and Y-score (partner→FGF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaCellular response to type III interferon →-0.223-1.428.007.00133
LUNG_SCLCResponse to hydrostatic pressure →+0.158+1.518.003.00833
BLOOD_LymphomaType III interferon-mediated signaling pathway →-0.223-1.428.007.00133
LUNG_NSCLC_LUADProtein localization to cytoskeleton →-0.058-1.548.005.00433
LUNG_NSCLC_LUADRegulation of epidermal cell differentiation →+0.113+2.009.002.00633
BLOOD_LeukemiaNeuron migration →-0.071-1.953.007.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 439 associations by consensus.

Cellular response to type III interferon by FGF11 expression — BLOOD_Lymphoma

Box plot of Cellular response to type III interferon in FGF11-low vs FGF11-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration