FGF1

Across TCGA patient cohorts, FGF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,812 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FGF1-associated proteins across cancer lineages are SEPTIN11, SRPX2, and TGFBI. Each is linked with FGF1 in more than 8 cancer types. Because this analysis shows association rather than direction, both FGF1-to-partner and partner-to-FGF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGF1 versus SEPTIN11 in BRCA, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF1→partner) and Y-score (partner→FGF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEPTIN11 →	+0.376	+0.986	<.001	<.001	3	9
BRCA	SRPX2 →	+1.016	+1.182	<.001	<.001	3	9
CCRCC	TGFBI →	+0.702	+0.919	.001	<.001	3	8
OV	THY1 →	+0.671	+1.123	<.001	<.001	3	8
OV	TNC →	+1.124	+1.487	<.001	<.001	3	8
CCRCC	PDLIM4 →	+0.686	+0.816	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,812 associations by consensus.

FGF1 vs SEPTIN11 — BRCA

Explore this scatter interactively →