FGF1

Across TCGA cell cohorts, FGF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,916 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FGF1-associated GO terms across cancer lineages are Dentinogenesis, Peptidyl-lysine oxidation, and Protein depolymerization. Each is linked with FGF1 in more than 11 cancer types. Because this analysis shows association rather than direction, both FGF1-to-partner and partner-to-FGF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dentinogenesis grouped by FGF1-low versus FGF1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF1→partner) and Y-score (partner→FGF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Dentinogenesis →	+1.893	+1.941	<.001	<.001	3	12
BONE	Peptidyl-lysine oxidation →	+1.225	+1.801	<.001	<.001	3	12
PANCREAS	Protein depolymerization →	+0.087	+0.403	<.001	.002	3	11
BONE	Regulation of mesenchymal stem cell proliferation →	+0.236	+1.613	<.001	<.001	3	10
BONE	Positive regulation of mesenchymal stem cell proliferation →	+0.236	+1.613	<.001	<.001	3	10
LIVER	Positive regulation of cytoskeleton organization →	+0.072	+1.835	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,916 associations by consensus.

Dentinogenesis by FGF1 expression — BONE

Explore this box plot interactively →