FGD6

Across TCGA patient cohorts, FGD6 mutation is significantly associated with the RNA expression of many other genes, with 6,956 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FGD6-associated genes across cancer lineages are FTH1P9, HOXC10, and LINC01072. Each is linked with FGD6 in more than 3 cancer types. Because this analysis shows association rather than direction, both FGD6-to-partner and partner-to-FGD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FTH1P9 grouped by FGD6-low versus FGD6-high in KIRC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGD6→partner) and Y-score (partner→FGD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	FTH1P9 →	+0.092	+4.708	<.001	.005	3	4
UCEC	HOXC10 →	+1.152	+1.385	.001	.009	3	4
CESC	LINC01072 →	+0.269	+4.345	<.001	.002	3	3
CESC	BNIP3P2 →	+0.054	+5.252	<.001	.002	3	3
CESC	TRIM53CP →	+1.722	+4.824	<.001	<.001	3	3
CESC	LINC02277 →	+0.079	+3.996	.002	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,956 associations by consensus.

FTH1P9 by FGD6 expression — KIRC

Explore this box plot interactively →