FGD5

Across TCGA cell cohorts, FGD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,311 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FGD5-associated GO terms across cancer lineages are Regulation of DNA repair, Mitotic cytokinesis, and Lipid modification. Each is linked with FGD5 in more than 6 cancer types. Because this analysis shows association rather than direction, both FGD5-to-partner and partner-to-FGD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by FGD5-low versus FGD5-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGD5→partner) and Y-score (partner→FGD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of DNA repair →	+0.037	+0.289	<.001	.006	3	7
UPPER_AERODIGESTIVE_TRACT	Mitotic cytokinesis →	+0.067	+0.066	<.001	.007	3	5
UPPER_AERODIGESTIVE_TRACT	Lipid modification →	+0.041	+0.067	.003	.005	3	5
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.133	+0.070	<.001	.004	3	5
UPPER_AERODIGESTIVE_TRACT	Stress granule assembly →	+0.104	+0.076	<.001	.001	3	5
OVARY	Epigenetic regulation of gene expression →	+0.076	+0.391	<.001	.008	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,311 associations by consensus.

Regulation of DNA repair by FGD5 expression — OVARY

Explore this box plot interactively →