FGD4

Across TCGA patient cohorts, FGD4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,719 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FGD4-associated proteins across cancer lineages are DNAJC2, DDAH1, and HAAO. Each is linked with FGD4 in more than 4 cancer types. Because this analysis shows association rather than direction, both FGD4-to-partner and partner-to-FGD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGD4 versus DNAJC2 in LSCC, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FGD4→partner) and Y-score (partner→FGD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DNAJC2 →	-0.352	-0.421	<.001	.003	3	4
LSCC	DDAH1 →	+0.485	+0.542	<.001	<.001	3	4
BRCA	HAAO →	+0.481	+0.541	.001	<.001	3	4
GBM	KCTD12 →	+0.557	+0.570	<.001	<.001	3	4
LUAD	MRPL3 →	-0.306	-0.602	<.001	<.001	3	4
LSCC	MRPS23 →	-0.308	-0.352	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,719 associations by consensus.

FGD4 vs DNAJC2 — LSCC

Explore this scatter interactively →