FEZ2

Across TCGA patient cohorts, FEZ2 protein abundance is significantly associated with the protein abundance of many other proteins, with 12,878 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FEZ2-associated proteins across cancer lineages are HEATR5A, SCFD1, and ZFYVE1. Each is linked with FEZ2 in more than 6 cancer types. Because this analysis shows association rather than direction, both FEZ2-to-partner and partner-to-FEZ2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FEZ2 versus HEATR5A in LUAD, with a Pearson correlation of 0.75.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FEZ2→partner) and Y-score (partner→FEZ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HEATR5A →	+0.345	+0.313	<.001	<.001	3	7
BRCA	SCFD1 →	+0.300	+0.342	<.001	<.001	3	4
COAD	ZFYVE1 →	+0.351	+0.373	<.001	<.001	3	4
BRCA	SNX12 →	+0.252	+0.249	<.001	<.001	3	4
BRCA	PSMC3 →	+0.188	+0.249	<.001	<.001	3	4
BRCA	SIN3A →	-0.256	-0.329	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,878 associations by consensus.

FEZ2 vs HEATR5A — LUAD

Explore this scatter interactively →