FETUB

Across TCGA patient cohorts, FETUB mutation is significantly associated with the RNA expression of many other genes, with 2,143 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FETUB-associated genes across cancer lineages are PSAT1P4, RNU6-222P, and RNU6-451P. Each is linked with FETUB in more than 2 cancer types. Because this analysis shows association rather than direction, both FETUB-to-partner and partner-to-FETUB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSAT1P4 grouped by FETUB-low versus FETUB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FETUB→partner) and Y-score (partner→FETUB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PSAT1P4 →	+0.142	+2.264	.001	<.001	3	3
UCEC	RNU6-222P →	+0.485	+2.224	<.001	.002	3	2
BRCA	RNU6-451P →	+0.404	+5.409	<.001	.005	3	2
BRCA	MRPS17P3 →	+0.131	+5.409	<.001	.005	3	2
LUAD	MIR496 →	+0.267	+6.333	<.001	<.001	3	2
LUAD	MIR4688 →	+0.494	+5.037	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,143 associations by consensus.

PSAT1P4 by FETUB expression — UCEC

Explore this box plot interactively →