FERMT2

Across TCGA patient cohorts, FERMT2 mutation is significantly associated with the RNA expression of many other genes, with 782 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FERMT2-associated genes across cancer lineages are TRIM48, VN1R6P, and MBD3L3. Each is linked with FERMT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FERMT2-to-partner and partner-to-FERMT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM48 grouped by FERMT2-low versus FERMT2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FERMT2→partner) and Y-score (partner→FERMT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TRIM48 →	+1.258	+3.966	<.001	.001	3	2
CESC	VN1R6P →	+0.030	+4.144	<.001	.009	3	2
CESC	MBD3L3 →	+0.307	+4.144	<.001	.009	3	2
CESC	RN7SKP171 →	+0.108	+6.174	<.001	<.001	3	2
CESC	LINC01399 →	+0.353	+3.874	<.001	.004	3	2
CESC	LINC01794 →	+0.042	+5.164	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 782 associations by consensus.

TRIM48 by FERMT2 expression — CESC

Explore this box plot interactively →