FERD3L

Across TCGA patient cohorts, FERD3L mutation is significantly associated with the RNA expression of many other genes, with 1,995 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FERD3L-associated genes across cancer lineages are TMEM38B, NKG7, and RITA1. Each is linked with FERD3L in more than 2 cancer types. Because this analysis shows association rather than direction, both FERD3L-to-partner and partner-to-FERD3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM38B grouped by FERD3L-low versus FERD3L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FERD3L→partner) and Y-score (partner→FERD3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TMEM38B →	+0.596	+2.081	.001	.001	3	3
UCEC	NKG7 →	+0.993	+2.470	.001	<.001	3	3
UCEC	RITA1 →	+0.464	+2.523	<.001	<.001	3	3
BLCA	RNU7-160P →	+1.456	+3.937	<.001	.007	3	3
UCEC	SETD3 →	+0.421	+3.828	<.001	<.001	3	3
UCEC	RPL4P4 →	+0.464	+2.000	.008	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,995 associations by consensus.

TMEM38B by FERD3L expression — UCEC

Explore this box plot interactively →