FER1L5

Across TCGA patient cohorts, FER1L5 mutation is significantly associated with the total protein of many other genes, with 73 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FER1L5-associated genes across cancer lineages are Rad50, ATM, and Caspase-7-cleavedD198. Each is linked with FER1L5 in more than 2 cancer types. Because this analysis shows association rather than direction, both FER1L5-to-partner and partner-to-FER1L5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rad50 grouped by FER1L5-low versus FER1L5-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FER1L5→partner) and Y-score (partner→FER1L5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Rad50 →	-0.359	-2.584	<.001	.009	3	3
COAD	ATM →	-0.472	-3.459	.001	.004	3	3
COAD	Caspase-7-cleavedD198 →	+1.132	+3.476	<.001	.002	3	3
UCEC	Cyclin-B1 →	+0.562	+4.169	<.001	<.001	3	3
UCEC	eIF4E →	+0.195	+1.628	<.001	<.001	3	2
UCEC	FoxM1 →	+0.186	+1.672	.007	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 73 associations by consensus.

Rad50 by FER1L5 expression — COAD

Explore this box plot interactively →