FER1L4

Across TCGA pan-cancer cohorts, FER1L4 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FER1L4 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher FER1L4 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FER1L4 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

PDAC, GBM, and LUAD are the cancer types where FER1L4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	II,III,IV	0.294	0.724	.022	15	view →
GBM	OS	Median	All	0.774	0.925	.002	6	view →
LUAD	OS	Median	II,III,IV	0.848	0.338	.019	5	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

FER1L4–PDAC (DFS)

Open the PDAC breakdown →