FEM1C

Across TCGA patient cohorts, FEM1C protein abundance is significantly associated with the RNA expression of many other genes, with 3,214 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FEM1C-associated genes across cancer lineages are NAB1, LRFN5, and OXCT2. Each is linked with FEM1C in more than 1 cancer types. Because this analysis shows association rather than direction, both FEM1C-to-partner and partner-to-FEM1C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FEM1C versus NAB1 in UCEC, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FEM1C→partner) and Y-score (partner→FEM1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NAB1 →	-0.755	-0.487	.007	.006	3	2
UCEC	LRFN5 →	-1.948	-0.589	.002	<.001	3	2
GBM	OXCT2 →	-0.564	-0.312	<.001	.004	3	2
LUAD	DEPDC7 →	-0.802	-0.376	.001	.001	3	2
GBM	RAPGEF4 →	-0.785	-0.450	.001	<.001	3	2
GBM	SLC39A14 →	+0.650	+0.281	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,214 associations by consensus.

FEM1C vs NAB1 — UCEC

Explore this scatter interactively →