FDX2

Across TCGA patient cohorts, FDX2 protein abundance is significantly associated with the protein abundance of many other proteins, with 15,156 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FDX2-associated proteins across cancer lineages are ACOT13, ATP5F1B, and GCSH. Each is linked with FDX2 in more than 7 cancer types. Because this analysis shows association rather than direction, both FDX2-to-partner and partner-to-FDX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FDX2 versus ACOT13 in PDAC, with a Pearson correlation of 0.64.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FDX2→partner) and Y-score (partner→FDX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ACOT13 →	+0.816	+0.893	<.001	<.001	3	8
BRCA	ATP5F1B →	+0.332	+0.471	<.001	<.001	3	8
BRCA	GCSH →	+0.532	+0.543	<.001	<.001	3	8
LSCC	NFS1 →	+0.352	+0.263	.001	<.001	3	8
UCEC	HIBADH →	+0.465	+0.447	<.001	<.001	3	7
CCRCC	ISCU →	+0.268	+0.289	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,156 associations by consensus.

FDX2 vs ACOT13 — PDAC

Explore this scatter interactively →