FDCSP

Across TCGA patient cohorts, FDCSP protein abundance is significantly associated with the RNA expression of many other genes, with 1,396 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FDCSP-associated genes across cancer lineages are SOS2, GNPNAT1, and CNIH1. Each is linked with FDCSP in more than 1 cancer types. Because this analysis shows association rather than direction, both FDCSP-to-partner and partner-to-FDCSP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FDCSP versus SOS2 in BRCA, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FDCSP→partner) and Y-score (partner→FDCSP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SOS2 →	-0.670	-1.975	.001	.008	3	1
BRCA	GNPNAT1 →	-0.862	-2.033	<.001	.003	3	1
BRCA	CNIH1 →	-0.553	-3.112	.009	<.001	3	1
BRCA	ATP6V1D →	-0.549	-2.757	.001	<.001	3	1
BRCA	VTI1B →	-0.463	-1.979	.003	.007	3	1
BRCA	DAAM1 →	-0.676	-1.949	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,396 associations by consensus.

FDCSP vs SOS2 — BRCA

Explore this scatter interactively →